SS 316L or SS 316Ti for freeze dryers
SS 316L or SS 316Ti for freeze dryers
(OP)
Hi Guys!
We are in the process of finalizing a lyophilizer for drying of our medicinal product. The equipment is subjected to extremes in temperature and pressure. During sterilization cycle, the pressure is about 1.2 bar and the temperature is 1210C and during drying, the pressure is 0.001 mBar and the temperature is -600C.
One manufacturer offers SS316L and other SS316Ti. SS316L is well known across the pharma industry and no problems with it. The manufacturer who is supplying SS 316Ti lyophilizer is a reputed and so does the other. Still, leg pulling seems to be obvious.
As SS316Ti contains 0.05% more carbon(this equipment has to undergo lot of welding), will this effect the life of the equipment? What are the other disadvantages you guys foresee? What advantages I have if I go for SS316Ti?
Thanks in advance,
We are in the process of finalizing a lyophilizer for drying of our medicinal product. The equipment is subjected to extremes in temperature and pressure. During sterilization cycle, the pressure is about 1.2 bar and the temperature is 1210C and during drying, the pressure is 0.001 mBar and the temperature is -600C.
One manufacturer offers SS316L and other SS316Ti. SS316L is well known across the pharma industry and no problems with it. The manufacturer who is supplying SS 316Ti lyophilizer is a reputed and so does the other. Still, leg pulling seems to be obvious.
As SS316Ti contains 0.05% more carbon(this equipment has to undergo lot of welding), will this effect the life of the equipment? What are the other disadvantages you guys foresee? What advantages I have if I go for SS316Ti?
Thanks in advance,





RE: SS 316L or SS 316Ti for freeze dryers
RE: SS 316L or SS 316Ti for freeze dryers
RE: SS 316L or SS 316Ti for freeze dryers
Thanks for the input. I did a lot of search regarding this during these 6 days but I couldn't get anything other than what you people indicated(perhaps my search tags are very weak). Though this is sufficient to impress my boss, I just like to know a little bit extra to my knowledge.
One of the webpages says "sensitization can be minimized either by reducing carbon content or by changing constituents of base metal". Can you guys, please, tell me by what mechanism Ti reduces sensitization though carbon content is high? Any links, will also help.
Thanks once again.
Regards,
RE: SS 316L or SS 316Ti for freeze dryers
RE: SS 316L or SS 316Ti for freeze dryers
RE: SS 316L or SS 316Ti for freeze dryers
Regards,
RE: SS 316L or SS 316Ti for freeze dryers
RE: SS 316L or SS 316Ti for freeze dryers
Regards,