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Steam flow to clean in place

Steam flow to clean in place

Steam flow to clean in place

(OP)
Hi all , there is a method to get the steam flow need to clean in place and sterlizate a given volumen at a vessel ?
It is a 85 litre free volumen.

The temperature to reach shall be 121 °C.

I have to determinate the flow and pressure of the Clean Steam Generator.


Pardal

RE: Steam flow to clean in place

It depends upon whether or not you require overkill approach. As a universal rule of thumb, 30Kgs of steam is considered for 1000 Liters (or 1 M3) volume. This for a sterilization time of 20 Minutes. So your flow rate will be 90Kgs/Hr. Generally you can get the temperature of 1210C at 2.1 Kg/Cm2 abs. but generally 2.5Kg/Cm2 abs. is used.

If your sterilizing temperature is 1350C, the sterilization time becomes 3 Minutes.

For steam sterilizers, total flow rate of 2.5Kgs/Hr is used for a volume of 27Liters at full loaded condition and the flow rate for chamber and jacket is 60% and 40% respectively.(The only proof is that I have my thumb well in place)

Note: Steam pressures can be obtained from steam tables.

Regards,

RE: Steam flow to clean in place

(OP)
I Quark:
Thanks for yours tips.
Could you submit to any other places or links to get more info.
Where I can get steam in place specifications.?
The use is for pharmaceutical industrie.
Thanks againg.


Pardal

RE: Steam flow to clean in place

Sartorius mastered this application. Check the website www.sartorius.com. If any of your colleagues is an ISPE (Internatinal Soceity for Pharmaceutical Engineers) member you will get ton loads of information (some are for free too)

Regards,

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